Chemical Information
Product Name BEC HCl CAS No. 222638-67-7
Molecular Weight 229.49 Molecular Formula C5H13BClNO4S
MOQ 100g Brand Biolang

Product Description

BEC HCl is a slow-binding and competitive Arginase II inhibitor with Ki of 0.31 μM (ph 7.5). target: Arginase II; In vitro: BEC HCl causes significant enhancement of NO-dependent smooth muscle relaxation in this tissue. BEC HCl enhances perivascular and peribronchiolar lung inflammation, mucus metaplasia, NF-κB DNA binding, and mRNA expression of the NF-κB-driven chemokine genes CCL20 and KC, and lead to further increases in airways hyperresponsiveness. In vivo: BEC HCl increased contractility in isolated myocytes from WT and NOS3 but not NOS1 knockout mice.

  •   Sales Center:1788 Cheng Xin Da Dao, Jiangning Qu, Nanjing Shi, Jiangsu Sheng, China
  •   +8615327198583

About Biolang

Shanghai Biolang Bio-Tech Co., Ltd., founded in 2004, located in Shanghai and Nanjing, R&D and logistics center located in Wuhan National Bioindustry Base,the production base in Luotian, Tongshan, Dongying, Pingxiang.Biolang is specialized manufacturer and supplier of New-Type pharmaceutical Raw Materials and Pharmaceutical Intermediates.