GW4064

Chemical Information
Product Name GW4064 CAS No. 278779-30-9
Molecular Weight 542.84 Molecular Formula C28H22Cl3NO4
MOQ 100g Brand Biolang

Product Description

GW 4064 is a potent FXR agonist with EC50 of 65 nM.
Treatment with different concentrations of GW4064 (1, 2.5, 5, 10 μM) reduces the lipid accumulation in the cells. Concordantly, GW4064 treatment significantly represses oleic acid-induced CD36 protein levels in a dose-dependent manner. Taken together, these data indicate that prevention of hepatic lipid accumulation is likely due to an inhibition of Cd36 expression by long-term GW4064 treatment.

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About Biolang

Shanghai Biolang Bio-Tech Co., Ltd., founded in 2004, located in Shanghai and Nanjing, R&D and logistics center located in Wuhan National Bioindustry Base,the production base in Luotian, Tongshan, Dongying, Pingxiang.Biolang is specialized manufacturer and supplier of New-Type pharmaceutical Raw Materials and Pharmaceutical Intermediates.